Receptor-targeted gene delivery viafolate-conjugated polyethylenimine
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چکیده
منابع مشابه
Mannose polyethylenimine conjugates for targeted DNA delivery into dendritic cells.
Cell surface-bound receptors represent suitable entry sites for gene delivery into cells by receptor-mediated endocytosis. Here we have taken advantage of the mannose receptor that is highly expressed on antigen-presenting dendritic cells for targeted gene transfer by employing mannosylpolyethylenimine (ManPEI) conjugates. Several ManPEI conjugates were synthesized and used for formation of Man...
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ژورنال
عنوان ژورنال: AAPS PharmSci
سال: 1999
ISSN: 1522-1059
DOI: 10.1208/ps010419